Many countries have banned travel from South Africa in an effort to stop the spread of the highly infectious 501Y.V2 variant, which is believed to have originated there and which is suspected to be more resistant to vaccines.
How have restrictions eased?
The country will remain in what is termed a level 3 lockdown, but a number of restrictions that had been in place will end.
Retail outlets can now sell alcohol between 10:00 and 18:00 from Monday to Thursday, and licensed outlets can serve drinks on-site from 10:00 to 22:00, when they must close.
Curfew hours will now be 23:00 to 04:00.
South Africans have faced three alcohol bans since the pandemic hit last March, the last was imposed on 28 December.
The government argues it was necessary to alleviate the pressure on the healthcare system.
The bans have not been popular among many in the public and the liquor industry said millions of jobs were at risk.
Announcing the latest changes, Mr Ramaphosa said: “I want to call on all of us to drink responsibly so that we do not experience a spike in trauma cases or an increase in infections due to reckless behaviour.”
In additional relaxations of rules, 50 people can now worship indoors and 100 outdoors.
Beaches, rivers, parks and swimming pools will reopen.
Mr Ramaphosa said the peak of the second wave of the virus had now passed, and that “the average rate of new infections has been steadily coming down over the last three weeks”.
He said: “These changes have been made possible by the significant reduction in Covid-19 hospital admissions across all provinces, reducing the pressure on beds and hospital personnel.”
Earlier, he had travelled to OR Tambo airport in Johannesburg to welcome the arrival of the Oxford-AstraZeneca doses, produced by the Serum Institute of India.
“The arrival of these vaccines contains the promise that we can turn the tide on this disease that has caused so much devastation and hardship in our country and across the world,” he said.
The one million doses will be given to healthcare workers, although no date has been set for the start of the roll-out, and the number is still short of that needed just for the country’s 1.25 million health workers.
The country says it has negotiated access to more than 50 million doses and has set a target of inoculating 40 million people, two-thirds of the population, this year.
Mr Ramaphosa pledged to “leave no stone unturned” to reach herd immunity.